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Nguyen T.T. Thuong on Muck Rack

Nguyen T.T. Thuong

As seen in: BioRxiv
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Articles

Disruption of Aldehyde Dehydrogenase 2 protects against 1 bacterial infection

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By Sam Berry, Xuling Chang, Scott Espich, Nguyen T.T. Thuong
| BioRxiv
Abstract The ALDH2*2 (rs671) allele is one of the most common genetic mutations in humans, yet the positive evolutionary selective pressure to maintain this mutation is unknown, despite its association with adverse health outcomes. ALDH2 is responsible for the detoxification of metabolically produced aldehydes, including lipid-peroxidation end products derived from inflammation.
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