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Nho Cong Luong on Muck Rack

Nho Cong Luong

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HELZ is a RNA-DNA helicase that resolves R loops to facilitate homologous recombination repair

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By Ramona Haji-Seyed-Javadi, Allyson E. Koyen, Sandip K Rath, Bo Wu, Matthew Z. Madden, Yingzi Hou, Priya Kapoor-Vazirani, Roshika Roshika, Meili Aiello, Wei-Che Tseng, Fatmata Sesay, John Kim, Tony Xing Tan, Seohyun C. Kim, Boya Gao, Anna M. Kenney, Erin Connolly Verified, Lily Yang, Blerta Xhemalce, Xiaoxian Li, Jeffrey M. Switchenko, Xiaofeng Yang, Zachary S. Buchwald, Xingming Deng, Kyle Miller, Bing Yao, Weixing Zhao, David Yu, Nho Cong Luong
| Nature Verified
Abstract R loop homeostasis is critical for DNA double-strand break (DSB) repair; however, how R loops are resolved in this context is poorly understood. Here, we define HELZ as a unique RNA-DNA helicase that resolves R loops to facilitate homologous recombination (HR) repair.
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