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Gene therapy with autologous hematopoietic stem cells has been investigated as an alternative to allogeneic hematopoietic stem-cell transplantation. 11-13 In the initial proof-of-principle, single-center study, four boys with cerebral adrenoleukodystrophy received autologous CD34+ hematopoietic stem cells transduced ex vivo with a lentiviral vector CG1711hALD that contained ABCD1 complementary DNA (cDNA).
“So we beat on, boats against the current, borne back ceaselessly into the past.”F. Scott Fitzgerald’s closing words in “The Great Gatsby” came to mind Thursday when I heard the news that St. Louis Collector of Revenue Gregory F.X. Daly would not be running for mayor. Once again, St. Louis is looking forward, but heading into the past.What is Tishaura Jones to do?
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