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Nicholas Lorig-Roach on Muck Rack

Nicholas Lorig-Roach

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Articles

Rapid and sensitive detection of SARS-CoV-2 antibodies by biolayer interferometry

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By John V. Dzimianski, Sara O’Rourke, David Alexander, Nicholas Lorig-Roach
| Nature Verified
Abstract Serological testing to evaluate antigen-specific antibodies in plasma is generally performed by rapid lateral flow test strips that lack quantitative results or by high complexity immunoassays that are time- and labor-intensive but provide semi-quantitative results. Here, we describe a novel application of biolayer interferometry for the rapid detection of antigen-specific antibody levels in plasma samples, and demonstrate its utility for quantification of SARS-CoV-2 antibodies.
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