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Nico A Carlson on Muck Rack

Nico A Carlson

As seen in: BioRxiv
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Phages carry orphan antitoxin-like enzymes to neutralize the DarTG1 toxin-antitoxin defense system

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By Michele LeRoux, Anna Johannesman, Nico A Carlson
| BioRxiv
Abstract The astounding number of anti-phage defenses encoded by bacteria is countered by an elaborate set of phage counter-defenses, though their evolutionary origins are often unknown. Here, we discover an orphan antitoxin counter-defense element in T4-like phages that can overcome the bacterial toxin-antitoxin phage defense system, DarTG1.
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