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Nicolas Anselmino on Muck Rack

Nicolas Anselmino

As seen in: Nature, Wiley Online Library, Texas Medical Center
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Articles

Role of the cross-regulation between Wnt pathway activation and androgen receptor signaling in prostate cancer treatment resistance

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By Nicolas Anselmino, Pablo Sanchis, Juan Bizzotto, Estefania Labanca, Jiabin Dong, Peter Shepherd, Jun Yang, Elba Vazquez, Joaquin Mateo, Geraldine Gueron, Christopher J. Logothetis
| Nature Verified
Abstract Prostate cancer (PCa) is a biologically heterogeneous disease that frequently progresses to castration-resistant prostate cancer (CRPC), a challenging clinical stage. The underlying mechanisms driving CRPC progression and resistance to androgen receptor (AR) signaling inhibition (ARSI) remain incompletely understood. Emerging evidence implicates the canonical Wnt pathway as a key contributor to CRPC progression.
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"Integrative Molecular Analyses of the MD Anderson Prostate Cancer Pati" by Nicolas Anselmino, Estefania Labanca et al.

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By Nicolas Anselmino, Estefania Labanca, Jiabin Dong, Jun Yang
| Texas Medical Center
PURPOSE: Develop and deploy a robust discovery platform that encompasses heterogeneity, clinical annotation, and molecular characterization and overcomes the limited availability of prostate cancer models.
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Defining the challenges and opportunities for using patient‐derived models in prostate cancer research

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By W. Nathaniel Brennen, Clémentine Le Magnen, Sofia Karkampouna, Nicolas Anselmino
| Wiley Online Library Verified
1 INTRODUCTION Prostate cancer is a global health issue with ~1,400,000 diagnoses and 375,000 deaths each year.1 The scale of this challenge requires international research efforts to uncover the underlying biology of prostate cancer across the disease trajectory. The new insights in prostate cancer biology can then be used to develop novel and more effective treatments for patients.
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