Nicole van Klink

Ictal-interictal SPECT analyzed by SPM (ISAS) with a public control database showed more localized results than subtraction ictal SPECT co-registered to MRI (SISCOM). The conclusion of ISAS and SISCOM was the same in 54% of datasets. SISCOM localized correctly in 55% and ISAS in 65%. ISAS results were easier to interpret than SISCOM results.

Abstract Candidates for epilepsy surgery must undergo presurgical evaluation to establish whether and how surgical treatment can stop seizures without causing neurological deficits. Various techniques, including MRI, PET, single-photon emission CT, video-EEG, magnetoencephalography and invasive EEG, aim to identify the diseased brain tissue and the involved network.