Nil Azra Aytekin on Muck Rack

Nil Azra Aytekin

As seen in: Taylor & Francis Online
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Articles

Gemcitabine-loaded Ca2+-crosslinked high-amylose starch beads as intratumoral depot candidates: microporosity, release, and in vitro activity

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By Deniz Ceylan, Hakan Avcı, Nil Azra Aytekin
| Taylor & Francis Online
Abstract Pancreatic ductal adenocarcinoma (PDAC) motivates localized drug-delivery strategies that increase intratumoral exposure while limiting systemic toxicity. Here, we report spherical high-amylose starch beads prepared by droplet gelation and Ca2+ ionotropic crosslinking as a simple, water-based depot platform. The beads preserved spherical geometry and displayed an interconnected microporous interior by SEM.
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