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Niles A. Pierce on Muck Rack

Niles A. Pierce

As seen in: ACS Publications, BioRxiv, The Salt Lake Tribune
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Articles

Models and Algorithms for Equilibrium Analysis of Mixed-Material Nucleic Acid Systems

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By Avinash Nanjundiah, Mark E. Fornace, Samuel J. Schulte, Niles A. Pierce
| ACS Publications
Abstract Click to copy section linkSection link copied! Dynamic programming algorithms within the NUPACK software suite enable analysis of equilibrium base-pairing properties for complex and test tube ensembles containing arbitrary numbers of interacting nucleic acid strands. Currently, calculations are limited to single-material systems that are either all-RNA or all-DNA.
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HCR spectral imaging: 10-plex, quantitative, high-resolution RNA and protein imaging in highly autofluorescent samples

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By Samuel J. Schulte, Mark E. Fornace, John Hall, Niles A. Pierce
| BioRxiv
Abstract Signal amplification based on the mechanism of hybridization chain reaction (HCR) provides a unified framework for multiplex, quantitative, high-resolution imaging of RNA and protein targets in highly autofluorescent samples. With conventional bandpass imaging, multiplexing is typically limited to four or five targets due to the difficulty in separating signals generated by fluorophores with overlapping spectra.
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Europe can pay for their own security. We should get out of the NATO trap.

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By Niles A. Pierce
| The Salt Lake Tribune Verified
It's well past time for the United States to take a new look at our NATO membership and see if it really serves our best security interests. NATO was formed in 1949 with the aim of containing Soviet expansion in Western Europe. The military premise of the alliance was that an attack on any member was an attack on all, and a collective response would deter war. This worked out pretty well. Protected by our nuclear and conventional military power, Western Europe recovered and prospered.
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