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Nilmar RS Moretti on Muck Rack

Nilmar RS Moretti

As seen in: BioRxiv
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Articles

SARS-CoV-2 reshapes m⁶A methylation in long non-coding RNAs of human lung cells

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By Cristina M. Peter, Fernando Antoneli, Caio O Cyrino, Nilmar RS Moretti
| BioRxiv
Abstract N6-Methyladenosine (m6A) is a key base modification that regulates RNA stability and translation during viral infection. While m6A methylation of host mRNAs has been studied in SARS-CoV-2-infected cells, its role in long non-coding RNAs (lncRNAs) is unknown. Here, we analyzed direct RNA sequencing (dRNA-seq) data from infected human lung cells (Calu-3) using a machine learning m6A detection framework.
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