Nilofer Husnoo

In a study in the ‘pre-biological’ era, most patients with a previous ileocolic resection for Crohn's disease would have preferred earlier surgery. Our contemporary data show that a smaller but significant proportion (>40%) still wish they had surgery sooner, highlighting a need for shared decision-making regarding optimal timing of surgery.

Loading metrics Open Access Study Protocol Citation: Husnoo N, Henderson I, Khattak H, Rea B, Wright C, Narice B, et al. (2025) Management of acute appendicitis in pregnancy (MAMA): Protocol for a multicentre observational study. PLoS One 20(8): e0330502.

Surgery is still considered late in the treatment of isolated terminal ileal Crohn's disease despite the evidence in favour of earlier resection. This study highlights key barriers to surgery from the clinician's perspective, which should be considered when designing local inflammatory bowel disease services and when designing future trials. INTRODUCTION Crohn's disease (CD) most commonly affects the terminal ileum (TI), with or without caecal involvement.