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Articles by Nina Schrand
E. coli Plasmid DNA Production Using The DASbox® Mini Bioreactor System
By Nina Schrand and Ma Sha, Eppendorf In recent years, the need for improved high-yield plasmid DNA production strategies has significantly increased due to its application in the field of messenger RNA (mRNA) vaccines and gene therapy.
E. coli Plasmid DNA Production Using The DASbox® Mini Bioreactor System
By Nina Schrand and Ma Sha, Eppendorf In recent years, the need for improved high-yield plasmid DNA production strategies has significantly increased due to its application in the field of messenger RNA (mRNA) vaccines and gene therapy.
Anaerobic Clostridium Beijerinckii Fermentation In Small- Scale Bioreactor Control Systems
By Ying Yang, Robert Glaser, Nina Schrand, and Ma Sha To demonstrate the feasibility of conducting anaerobic fermentation in Eppendorf small scale fermenters, we grew the obligate anaerobe Clostridium beijerinckii, a natural producer of butanol and isopropanol, in BioBLU® f Single-Use Vessels controlled by the DASbox® Mini Bioreactor and DASGIP® Parallel Bioreactor Systems.
PID Controlled Constant RQ Fermentation Of Pichia Pastoris In The DASbox® Mini Bioreactor System
By Nina Schrand, Malte Schneider, Ma Sha Compared to mammalian cell culture, Pichia pastoris displays a much faster growth and requires less expensive growth medium, making it ideal for protein production in bioreactors. For optimizing the production yield of a P. pastoris culture, one of the most important factors is the feeding strategy.
A Guide To Pichia Pastoris Fermentation In Single-Use Stirred-Tank Bioreactors
By Ying Yang, Nina Schrand, and Ma Sha Pichia pastoris is a methylotrophic yeast largely used for heterologous protein production in biotechnology. As an expression system, the main advantages of P. pastoris over E. coli are that the eukaryotic P. pastoris is capable of carrying out post-translational modifications, such as glycosylation, and meanwhile secreting the protein of interest. Compared to mammalian cell culture, P.
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