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Ying Yang on Muck Rack

Ying Yang

As seen in: Environmental Health Perspectives, Forbes, Arthritis & Rheumatology, British Journal of Cancer, Color Research & Application, Nature, Wiley, Wiley Online Library, arXiv, British Pharmacological Society and
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Articles

The efficacy and safety of pembrolizumab in the treatment of HER2-negative advanced gastric or gastroesophageal junction cancer: a systematic review and meta-analysis of emerging clinical data

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By Ying Yang, Lingli Jiang, Genming Zhang, Ke Li, Daorui Li
| Frontiers in Immunology
Abstract Introduction: Pembrolizumab, an immune checkpoint inhibitor (ICI) targeting programmed cell death protein 1 (PD-1), has demonstrated significant clinical value in the treatment of human epidermal growth factor receptor 2 (HER2)-negative advanced gastric cancer (GC) and gastroesophageal junction cancer (GEJC).
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An interpretable XGBoost model for contrast-associated acute kidney injury in patients with acute coronary syndrome: development and geographical external validation

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By Chuanwei Zhao, HongLin Li, Yane Yang, Ying Yang, Xinhua Wu
| Frontiers in Digital Health
Abstract Background: Contrast-associated acute kidney injury (CA-AKI) is a clinically relevant complication after coronary angiography in patients with acute coronary syndrome (ACS). We aimed to develop and geographically validate a compact, interpretable machine-learning model and to determine whether the nonlinear algorithm provided incremental value beyond conventional regression using the same predictors.
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Asymmetric RBBP7 regulates the first cell fate decision of early mammalian embryos

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By Xiao Han, Heng-Ji Xu, Meng-Xia Liu, Yanchen Liu, Yu-Ting Cai, Yu-Sheng Chen, Chun-Chun Gao, Yong-liang Zhao, Xiu-Jie Wang, Dangsheng Li, Xiang Zhou, Ying Yang, Jianyong Han, Yun-Gui Yang, Lin-Fang Ju, Danru Zhang, Shaokang Jia
| Nature Verified
Abstract Asymmetric transcription of noncoding RNA LincGET is currently recognized as the earliest event regulating the first cell fate decision in mammalian embryogenesis. However, whether key protein factors modulate this process remains elusive. Here, we identify RBBP7 as the earliest protein factor regulating developmental cell fate in mammals. Loss of RBBP7 drives cells towards ICM lineage.
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