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Ninso Matsunaga on Muck Rack

Ninso Matsunaga

As seen in: International Journal of Cardiology
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Articles

Exacerbation of autoimmune myocarditis by an immune checkpoint inhibitor is dependent on its time of administration in mice

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By Kenjiro Tsuruoka, Shigeo Wakabayashi, Hirofumi Morihara, Ninso Matsunaga
| International Journal of Cardiology Verified
Highlights • We developed a mouse experimental autoimmune myocarditis (EAM) model. • Exacerbation of autoimmune myocarditis by an immune checkpoint inhibitor (ICI) is dependent on its time of administration in mice. • The appearance of ICI-induced autoimmune myocarditis is related to autoimmune system activity before ICI administration. • We propose that ICI administration should be avoided in patients with autoimmune disorders.
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