Niveditha Nerlakanti on Muck Rack

Niveditha Nerlakanti

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Articles

The bone ecosystem facilitates multiple myeloma relapse and the evolution of heterogeneous drug resistant disease - Nature Communications

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By Ryan Bishop, Anna Miller, Niveditha Nerlakanti, Jeremy Frieling, Praneeth Sudalagunta, Conor Lynch , Rafael R. Canevarolo
| Nature
Abstract Multiple myeloma (MM) is an osteolytic malignancy that is incurable due to the emergence of treatment resistant disease. Defining how, when and where myeloma cell intrinsic and extrinsic bone microenvironmental mechanisms cause relapse is challenging with current biological approaches. Here, we report a biology-driven spatiotemporal hybrid agent-based model of the MM-bone microenvironment.
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