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Articles

NMR-based metabolomic analysis identifies RON-DEK-β-catenin dependent metabolic pathways and a gene signature that stratifies breast cancer patient survival

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By Brian Hunt, Sara Vicente-Muñoz, NMR-Metabolomics Core, Taylor E. Lange
| PLOS
Loading metrics Open Access Peer-reviewed Research Article Abstract Background Advances in detection techniques and treatment have increased the diagnosis of breast cancer at early stages; however, recurrence occurs in all breast cancer subtypes, and both recurrent and de novo metastasis are typically treatment resistant. A growing body of evidence supports the notion that metabolic plasticity drives cancer recurrence.
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