Nobuaki Matsubara
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PARP and Androgen-Signaling Inhibition plus ADT in Metastatic Prostate Cancer.
A previous trial involving patients with metastatic prostate cancer that was resistant to androgen pathway modulation (formerly referred to as castration-resistant) showed that adding talazoparib to enzalutamide significantly improved imaging-based progression-free survival and overall survival, with the greatest benefit observed in the cohort with alterations in homologous recombination repair genes.
First-In-Human Study: Dose Expansion of E7130 in Urothelial Carcinoma and Squamous Cell Carcinoma of the Head and Neck
BOR best overall response CAF cancer-associated fibroblast CBR clinical benefit rate CI confidence interval CR complete response CTCAE National Cancer Institute Common Terminology Criteria for Adverse Events DCE-MRI dynamic contrast-enhanced MRI DCR disease control rate DEGs differentially expressed genes DLT dose-limiting toxicity DOR duration of response ECLIA electrochemiluminescence immunoassay ECOG PS Eastern Cooperative Oncology Group performance status FDR false discovery rate GSEA...
Patient-reported outcomes in TALAPRO-2 trial: addressing data integrity and comparative clinical benefit in mCRPC
Have a website account?Log In orRegister for exclusive website content. Home / Vol 15, No 1 (February 28, 2026) / Patient-reported outcomes in TALAPRO-2 trial: addressing data integrity and comparative clinical benefit in mCRPC PDF 1 views Full Text 1 views COI Form 3 views Session Timed Out Your session has expired. Please sign in again.
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