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Noelle Neighbarger

As seen in: BioRxiv
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Articles

Locus coeruleus injury modulates ventral midbrain neuroinflammation during DSS-induced colitis

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By Jake Sondag Boles, Jenny Holt, Cassandra Cole, Noelle Neighbarger
| BioRxiv
Abstract Parkinson's disease (PD) is characterized by a decades-long prodrome, consisting of a collection of non-motor symptoms that emerges prior to the motor manifestation of the disease. Of these non-motor symptoms, gastrointestinal dysfunction and deficits attributed to central norepinephrine (NE) loss, including mood changes and sleep disturbances, are frequent in the PD population and emerge early in the disease.
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The R1441C-LRRK2 mutation induces myeloid immune cell exhaustion in an age- and sex-dependent manner

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By Rebecca Wallings, Karen McFarland, Hannah Staley, Noelle Neighbarger
| BioRxiv
Abstract Considering age is the greatest risk factor for many neurodegenerative diseases, aging, in particular aging of the immune system, is the most underappreciated and understudied contributing factor in the neurodegeneration field. Genetic variation around the LRRK2 gene affects risk of both familial and sporadic Parkinson's disease (PD).
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The R1441C-LRRK2 mutation induces myeloid immune cell exhaustion in an age- and sex-dependent manner

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By Rebecca Wallings, Karen McFarland, Hannah Staley, Noelle Neighbarger
| uke.de
Research ExplorerPublicationsThe R1441C-LRRK2 mutation induces myeloid immune cell exhaus... Abstract Bibliographical data
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