Noravy Briere

AA African American Hgb F fetal hemoglobin HU hydroxyurea SCA sickle cell anemia 1 INTRODUCTION The Pediatric Sickle Cell Program of Northern Virginia recently published a 10-year analysis of uniform hydroxyurea (HU) implementation starting in infancy for all patients with sickle cell disease of severe genotype, referred to as sickle cell anemia (SCA).1 The HU implementation program targeted high fetal hemoglobin (Hgb F) with close adherence monitoring.