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Articles

A Comparative Study of Flash Nanoprecipitation and Sequential Nanoprecipitation: Impact of Formulation Parameters on Drug-Loaded Nanoparticle Formation

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By Nouha El Amri, Rachel Pollard, Parker Lewis, Amy McKinstry
| dx.doi.org
1. Introduction Click to copy section linkSection link copied! Polymeric nanoparticles have emerged as powerful vehicles for drug delivery, offering enhanced bioavailability, improved stability, and targeted delivery capabilities. (1,2) Despite their promise, clinical translation remains limited due in part to challenges in scaling synthesis processes while maintaining control over particle characteristics.
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Design of Modular, 3D‐Printed Millifluidic Mixers to Enable Sequential NanoPrecipitation (SNaP) for the Tunable Synthesis of Drug‐Loaded Nanoparticles and Microparticles

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By Parker Lewis, Thomas Y. Belinky, Nouha El Amri, Allie Karakosta LeMay
| pericles.pericles-prod.literatumonline.com
Conflict of Interest The authors declare no conflict of interest. Supporting Information Filename Description admt202400583-sup-0001-SuppMat.pdf4.3 MB Supporting Information References 1, , , , Annu. Rev. Chem. Biomol. Eng. 2010, 1, 149. 2, , , , , , , , , Mol. Pharmaceutics 2020, 17, 757. 3, , , , , , , , Nanoscale 2018, 10, 3307. 4, , , , , , , , , , , , , Nat. Mater. 2023, 22, 391. 5, , , , , , , , , , Nanoscale 2023, 15, 16016. 6, , , , , , , Eur. J. Pharm. Sci. 1998, 6, 153. 7, , , Nat. Mater. 2013, 12, 991.
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