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Nourice Jaber on Muck Rack

Nourice Jaber

As seen in: Frontiers in Immunology
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Articles

SEVI fibrils are induced by bacterial surface molecules and exert antimicrobial activity against ESKAPE pathogens

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By Verena Vogel, Lia-Raluca Olari, Richard Bauer, Sandra Burczyk, Fiona Witz, Ulrich Stifel, Julia Zinngrebe, Clarissa Read, Pamela Fischer-Posovszky, Thunchanok Thummaraj, Jan Münch, Barbara Spellerberg, Emely Walker, Nourice Jaber, Stefanie Mauerer, Ulrich Rupp, Annalena Kuhn
| Frontiers in Immunology
Abstract Introduction: Semen-derived enhancer of viral infection (SEVI) is an amyloid fibril formed from PAP248-286, a fragment of prostatic acid phosphatase naturally occuring in seminal plasma. Beyond its role in HIV transmission, SEVI may contribute to innate immunity. Since many amyloids display antimicrobial effects, we investigated its antibacterial activity against ESKAPE pathogens and urogenital bacteria.
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