Under a Creative Commons license open access Keywords Type 1 diabetes Tolerance T cell infiltrates Islets Neoepitopes Beta cells Abbreviations AIRE autoimmune regulator gene AAb autoantibody APCs antigen presenting cells APECED autoimmune polyendocrinopathy candidiasis dystrophy ChgA chromogranin A CHGA gene or transcript for ChgA CXCL10 C–X–C motif chemokine ligand 10 CXCR3 C–X–C Motif Chemokine Receptor 3 DR3 HLA DRA1∗01:01-DRB1∗03:01 DR4 HLA DRA∗01:01-DRB1∗04:01 DQ2 HLA...