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Articles

Assessment and Comparison of Early Developmental Toxicity of Six Per- and Polyfluoroalkyl Substances with Human Embryonic Stem Cell Models

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By Miaomiao Zhao, Nuoya Yin, Renjun Yang, Shichang Li
| dx.doi.org
Download Hi-Res ImageDownload to MS-PowerPointCite This:Environ. Sci. Technol. 2024, XXXX, XXX Terms & Conditions Most electronic Supporting Information files are available without a subscription to ACS Web Editions. Such files may be downloaded by article for research use (if there is a public use license linked to the relevant article, that license may permit other uses).
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Transcriptomic Integration Analyses Uncover Common Bisphenol A Effects Across Species and Tissues Primarily Mediated by Disruption of JUN/FOS, EGFR, ER, PPARG, and P53 Pathways

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By Renjun Yang, Yuanping Lu, Nuoya Yin, Francesco Faiola
| dx.doi.org
Download Hi-Res ImageDownload to MS-PowerPointCite This:Environ. Sci. Technol. 2023, XXXX, XXX Terms & Conditions Most electronic Supporting Information files are available without a subscription to ACS Web Editions. Such files may be downloaded by article for research use (if there is a public use license linked to the relevant article, that license may permit other uses).
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PFOA and PFOS Disrupt the Generation of Human Pancreatic Progenitor Cells

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By Shuyu Liu, Nuoya Yin, Francesco Faiola
| American Chemical Society
The two most infamous perfluoroalkyl acids, PFOA and PFOS, are persistent, widespread, bioaccumulative, and associated with many health issues. However, knowledge about their potential toxicity to the developing pancreas or their association with metabolic diseases, such as diabetes, in humans is limited. In this study, we investigated the effects of PFOA and PFOS on the in vitro generation of pancreatic progenitor cells from human embryonic stem cells, a process that mimics in vivo organogenesis.
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