Olatz Arnold-Garcia on Muck Rack

Olatz Arnold-Garcia

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Stathmin-2 loss leads to neurofilament-dependent axonal collapse driving motor and sensory denervation - Nature Neuroscience

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By Maximiliano Presa, Michael W. Baughn, Karen Ling, Cathleen M Lutz, Don W. Cleveland, Melinda S. Beccari, Olatz Arnold-Garcia, I. Sandra Ndayambaje
| Nature Verified
Abstract The mRNA transcript of the human STMN2 gene, encoding for stathmin-2 protein (also called SCG10), is profoundly impacted by TAR DNA-binding protein 43 (TDP-43) loss of function. The latter is a hallmark of several neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS).
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