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Oluyinka Opaleye

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Articles

Continental-scale genomic surveillance of Plasmodium falciparum malaria across sub-Saharan Africa with rapid nanopore sequencing

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By Mulenga Mwenda, Welmoed van Loon, Brenda Mambwe, Amy Gaye, Salma Suliman, Djiby Sow, Bassirou Ngom, Arsène Zongo, Sheila Otieno, Bixa Ogola, Manuela Carrasquilla, Torsten Feldt, Tafese Beyene Tufa, Rafael Oliveira, Christina Ntalla, Oumarou Ouédraogo, Kephas Otieno, Adekunle O. Olowe, Marley Gibbons, Chris Drakeley, Frank P. Mockenhaupt, Issiaka Soulama, Daouda Ndiaye, Olusola Ojurongbe, Simon Kariuki, Jonathan Schultz, Moonga B. Hawela, Daniel Bridges, Jason Hendry, Karolina Mosler, Bernd Bohmeier, Miriam Chomba, Adedolapo Olorunfemi, Nassandba Julien Yanogo, Fiyinfoluwa Ojeniyi, Etilé A. Anoh, Vincent Achi, Carol Chiyesu, Moussa Niangaly, Dagaga Kenea Goboto, Emma Schallenberg, Yuhana Sogoba, Oluyinka Opaleye, Grit Schubert
| Nature Verified
Abstract In sub-Saharan Africa, continental-scale genomic surveillance of Plasmodium falciparum malaria is needed to track the spread of drug and diagnostic resistance, as well as monitor parasite evolutionary responses to vaccine rollout. Yet continental-scale implementation is hindered by a lack of genomic approaches suitable for local laboratories, and the vastness of the continent. Here, we initiate a decentralised scale-up of P.
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