The results of this study suggest that the C-ISC-Q scale can be used to assess the quality of life of patients with intermittent catheterization of neurogenic bladder. The scale has high internal consistency and retest reliability, good content validity and calibration correlation validity. The scale has a moderate number of entries and an easy-to-understand presentation, and is rated on a 5-point Likert scale (0–4), with higher scores indicating higher quality of life.