Ombeline Rossier

arising from R. Ayala et al. Nature Communications https://doi.org/10.1038/s41467-023-43824-9 (2023) Electron cryo-microscopy (cryo-EM) has become a leading tool of structural biology, thanks to direct electron detectors and rapid progress in image analysis.

Abstract The promises of vaccines based on virus-like particles stimulate demand for universal non-infectious virus-like platforms that can be efficiently grafted with large antigens. Here, we harnessed the modularity and extreme affinity of the decoration protein pb10 for the capsid of bacteriophage T5.