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Ontlametse Thato Bareng on Muck Rack

Ontlametse Thato Bareng

As seen in: MDPI
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Articles

Vaccines | Free Full-Text | No Difference in the Prevalence of HIV-1 gag Cytotoxic T-Lymphocyte-Associated Escape Mutations in Viral Sequences from Early and Late Parts of the HIV-1 Subtype C Pandemic in Botswana

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By Baitshepi Mokaleng, Ontlametse Thato Bareng, Dorcas Maruapula, Doreen Ditshwanelo
| MDPI
Abstract : HIV is known to accumulate escape mutations in the gag gene in response to the immune response from cytotoxic T lymphocytes (CTLs). These mutations can occur within an individual as well as at a population level. The population of Botswana exhibits a high prevalence of HLA*B57 and HLA*B58, which are associated with effective immune control of HIV.
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