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Oreoluwa Kolade on Muck Rack

Oreoluwa Kolade

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Articles

Mesenchymal stromal cells immunosuppress osteoarthritis synovial fluid modulated monocytes via IL-6 and CCL2

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By Mozhgan Rasti, Aida Feiz Barazandeh, Shahrzad Nouri, Rachel Low, Kevin D. Fan, Rajiv Gandhi, Sowmya Viswanathan, Kevin P. Robb, Oreoluwa Kolade
| Nature Verified
Abstract Mesenchymal stromal cell (MSC) interactions with monocytes/macrophages are central to their therapeutic effects in knee osteoarthritis (KOA); however, mechanisms of these interactions are not fully understood. We hypothesize that MSC soluble factors, particularly interleukin-6 (IL-6) and C-C motif chemokine ligand (CCL2) modulate monocytes in KOA environment.
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