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Orgeta Zejneli

As seen in: BioRxiv
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Articles

Strategy of selection and optimization of single domain antibodies targeting the PHF6 linear peptide within the Tau intrinsically disordered protein

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By Orgeta Zejneli, Marine Bachelot Nguyen, François-Xavier Cantrelle, Justine Mortelecque
| BioRxiv
New Results doi: https://doi.org/10.1101/2023.07.18.549252 Abstract The use of VHHs (Variable domain of the Heavy-chain of the Heavy-chain-only antibodies) as disease-modifying biomolecules in neurodegenerative disorders holds promises including to target aggregation-sensitive proteins . Exploitation of their clinical values dependents however on the capacity to deliver VHHs with optimal physico-chemical properties for their specific context of use.
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By Niels Kruse, Peter Lange, Franc Llorens, Matthias Schmitz, Nadine Gotzmann, Ewa Golanska, Katrin Thüne, Orgeta Zejneli, Eirini Kanata, Tobias Knipper, Maria Cramm, Saima Zafar, Beata Sikorska, Pawel P. Liberski, Eva Mitrova, Daniela Varges, Christian Schm
| secure.jbs.elsevierhealth.com
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