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Loss of left ventricular rotation is a significant determinant of functional mitral regurgitation
Highlights • Cardiac MRI identifies diminished LV rotation as a novel pathophysiological correlate of functional mitral regurgitation. • Loss of apical rotation in this pathology may affect future evaluation and treatment. Abstract Aim To evaluate insufficient rotational movement of the left ventricle (LV) as a potential novel mechanism for functional regurgitation of the mitral valve (FMR).
Prevalence of left ventricular hypertrabeculation/noncompaction among patients with congenital dyserythropoietic anemia Type 1 (CDA1)
Highlights • CDA1 is a rare autosomal recessive disease. • CMR is routinely used to detect myocardial iron overload in CDA1 patients. • LVNC morphology was detected by CMR in most of our CDA1 patients. • The severity of LVNC was independent of myocardial iron levels. Abstract Background Congenital dyserythropoietic anemia type 1 (CDA1) is a rare autosomal recessive disease characterized by macrocytic anemia, ineffective erythropoiesis, and secondary hemochromatosis.
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