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Othman Baradwan

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Articles

Interkingdom Endodontic Biofilm Supernatant Induces a Biphasic Inflammatory and Metabolic Transcriptional Response in Dental Pulp Stem Cells In Vitro

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By Saeed Alqahtani, Sumaya Abusrewil, Othman Baradwan
| Wiley Online Library Verified
1 Introduction Dental pulp is a highly specialized connective tissue that is susceptible to inflammation triggered by microbial invasion, commonly through dental caries or trauma (Pohl et al. 2024). Microbial ingress into the pulp and root canal system initiates pulpitis, which may progress to necrosis and apical periodontitis. As pulpitis severity and clinical presentation are variable, contemporary management increasingly emphasizes preserving pulp vitality where possible.
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