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Ozlem Topaloglu on Muck Rack

Ozlem Topaloglu

As seen in: Color Research & Application, Memory Studies, Medscape
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Articles

A Meta-Analysis Evaluating the Incidence of Bleeding Events With Intravenous Defibrotide Treatment Outside the Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome Setting - William Tappe, Saurabh Aggarwal, Ozlem Topaloglu, Massimo Iacobelli, 2020

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By Saurabh Aggarwal, Ozlem Topaloglu, Massimo Iacobelli, William Tappe
| Memory Studies
Introduction Defibrotide (Defitelio) is a polydisperse mixture of predominately single-stranded polydeoxyribonucleotide sodium salts that has been shown in vitro to protect the endothelium from cytotoxic and inflammatory damage by reducing activation of endothelial cells.1–3 Preclinical data suggest that defibrotide reduces endothelial cell dysfunction by mechanisms that are antithrombotic, profibrinolytic, antiadhesive, and anti-inflammatory, thereby restoring the thrombotic-fibrinolytic...
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Early Biologic Treatment in Patients With Crohn's Disease

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By Ryan Ungaro, Saurabh Aggarwal, Ozlem Topaloglu, Wan-Ju Lee
| Medscape Verified
Table 1.
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Systematic review and meta‐analysis: efficacy and safety of early biologic treatment in adult and paediatric patients with Crohn’s disease

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By Ryan Ungaro, Saurabh Aggarwal, Ozlem Topaloglu, Wan‐Ju Lee
| Color Research & Application Verified
Summary Background There is an increasing body of evidence showing that earlier use of biologics improves clinical outcomes in Crohn's disease (CD). Aim To perform a systematic review and meta‐analysis to assess the impact of early biologic use in the treatment of CD. Methods PubMed and Embase databases were searched for English language papers and conference abstracts published through April 30, 2019.
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