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Özlem Yüce Petronczki on Muck Rack

Özlem Yüce Petronczki

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Articles

KRAS is required for plexiform neurofibroma formation and represents a targetable vulnerability in established tumors

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By Andrea Forero, Jo-Anne Wilson, Xuelong Jiang, Liang Hu, Niousha Ahmari, Jay Pundavela, Mi-Ok Kim, Eva Dombi, Jianqiang Wu, Julia Brunmair, Nancy Ratner, Abby Schaeper, Özlem Yüce Petronczki
| Science Magazine Verified
Abstract INTRODUCTION RESULTS DISCUSSION MATERIALS AND METHODS Acknowledgments Supplementary Materials REFERENCES Information & Authors Metrics & Citations View Options References Figures Tables Media Share This article has 0 eLetter . Abstract Patients with neurofibromatosis type 1 develop Schwann cell tumors called neurofibromas that arise within peripheral nerves, driven by loss of neurofibromin and consequent increased RAS/RAF/MEK signaling.
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