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P. Barton Duell on Muck Rack

P. Barton Duell

As seen in: Nature, Wiley Online Library, JAMA (The Journal of the American Medical Association), Healio Cardiology, Journal of Clinical Lipidology
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Articles

Update on familial hypercholesterolemia: an expert clinical consensus from the National Lipid Association

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By Marina Cuchel, P. Barton Duell, Robert A. Hegele, Lisa Caldwell Hudgins
| Journal of Clinical Lipidology Verified
Treatment LDL-C treatment goals for the prevention of cardiovascular disease have substantially intensified over the last 30 years, in large part thanks to the documented benefit of sequentially lower LDL-C levels for prevention of ASCVD events and the ongoing development of new lipid lowering drugs leading to the ability to reach lower LDL-C goals.
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Limitations of gene editing assessments in human preimplantation embryos - Nature Communications

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By Amy Koski, Crystal Van Dyken, Keliang Wu, Ying Gu, Yue Shen, Hui Yang, P. Barton Duell, Sanjiv Kaul, Jin-Soo Kim, Zi-Jiang Chen
| Nature Verified
Abstract Range of DNA repair in response to double-strand breaks induced in human preimplantation embryos remains uncertain due to the complexity of analyzing single- or few-cell samples. Sequencing of such minute DNA input requires a whole genome amplification that can introduce artifacts, including coverage nonuniformity, amplification biases, and allelic dropouts at the target site.
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Elevated LDL triglycerides tied to higher risk for ASCVD

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By Erik Swain Verified, Richard Smith, P. Barton Duell
| Healio Cardiology Verified
Source/Disclosures Disclosures: Balling reports no relevant financial disclosures. Please see the study for all other authors’ relevant financial disclosures. Duell reports receiving institutional grants from or consulting for Akcea/Ionis, Esperion, Kaneka, Novo Nordisk, Regeneron, Regenxbio and Retrophin/Travere. Source/Disclosures Disclosures: Balling reports no relevant financial disclosures. Please see the study for all other authors’ relevant financial disclosures.
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