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Pablo Barbeito on Muck Rack

Pablo Barbeito

As seen in: BioRxiv, eLife
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Articles

Formin-like 1β phosphorylation at S1086 is necessary for secretory polarized traffic of exosomes at the immune synapse in Jurkat T lymphocytes

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By Javier Ruiz-Navarro, Sara Fernández-Hermira, Pablo Barbeito, Irene Sanz-Fernández
| eLife
eLife Assessment This important study uses the Jurkat T cell model to study the role of Formin-like 1 β phosphorylation at S1086 on actin dynamics and exosome release at the immunological synapse. The evidence supporting these findings is compelling within the framework of the Jurkat model.
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Depletion of BBSome Subunits Alters Receptor Endocytosis and Promotes EMT via TGF-β Signaling

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By Carlos Solarat, Jose Barra-Carneiro, Sara Vila-Almuina, Pablo Barbeito
| BioRxiv
Abstract Ciliopathies are genetic disorders caused by defects in the structure or function of the cilia and their related structures. Bardet-Biedl syndrome (BBS) is a complex ciliopathy with varied symptoms, probably due to altered membrane receptor signalling pathways. This study explores the role of BBS1 and BBS4 gene deficiencies in receptor trafficking and epithelial-mesenchymal transition (EMT) in retinal epithelial cells.
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