Pablo Elías Morande on Muck Rack

Pablo Elías Morande

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Articles

Ibrutinib therapy downregulates AID enzyme and proliferative fractions in chronic lymphocytic leukemia

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By Mariela Sivina, Pablo Elías Morande, Angimar Uriepero, Noé Seija
| Blood Verified
Pablo Elías Morande, Mariela Sivina, Angimar Uriepero, Noé Seija, Catalina Berca, Pablo Fresia, Ana Inés Landoni, Javier M. Di Noia, Jan A. Burger and Pablo Oppezzo Blood 2019 133:2056-2068; doi: https://doi.org/10.1182/blood-2018-09-876292 Key Points AID protein expression and proliferative fractions are decreased during ibrutinib therapy in patients with CLL. Downregulation of AID and proliferative subsets are associated with decrease of AKT and JAK1/STAT6 signaling after ibrutinib therapy.
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