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Pablo Gomes Noleto

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Articles

Prime-pull immunisation with yeast-based vaccine modifies cell trafficking and T-cell immunity in bovine mammary gland

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By Patricia Cunha, Florence B. Gilbert, Pierre Germon, Pascal Rainard, Rodrigo Martins, Célya Danzelle, Pablo Gomes Noleto, Yves Le Vern, Olivier Boulesteix, Marc Blondel, Ignacio Caballero-Posadas
| Nature Verified
Abstract Mastitis remains a major challenge for the dairy industry and the limited efficacy of commercially available vaccines is attributed to their inability to induce strong local cell-mediated immunity. As alternatives, yeast shows great promise, acting as antigen vectors, production platforms and natural adjuvants inducing robust cellular responses.
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