Paige M. Steffen

Abstract Enhancers control the location and timing of gene expression and contain the majority of variants associated with disease1,2,3. The ZRS is arguably the most well-studied vertebrate enhancer and mediates the expression of Shh in the developing limb4. Thirty-one human single-nucleotide variants (SNVs) within the ZRS are associated with polydactyly4,5,6.

The Corporate Equality Index ( "CEI" ), an annual list published by the Human Rights Campaign ( "HRC" ) Foundation that rates workplaces on LGBTQ equality, recently released its 15th Edition, which reported that a record number of businesses are now embracing inclusive policies for LGBTQ employees.

Discrimination in the access to and the provision of healthcare has been, and continues to be, an unfortunate reality for the LGBTQ community that not only affects LGBTQ individuals themselves on a day-today basis, but also has a negative impact on their relationships and their families. Historically, the LGBTQ community has been disproportionately affected by discriminatory insurance practices and provider-level bias. Fortunately, within the past several years, notable progress has been made.