Paimon Goulart on Muck Rack

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vcfsim: flexible simulation of all-sites VCFs with missing data

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By Kieran Samuk, Paimon Goulart
| biorxiv.org
Abstract VCFs are the most widely used data format for encoding genetic variation. By design, standard VCFs do not include data from sites where all individuals are homozygous for the reference allele ("invariant sites") and thus do not differentiate these from sites where data are completely missing.
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