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Pak-Yin Lui

As seen in: The Journal of Immunology
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Articles

Middle East Respiratory Syndrome Coronavirus ORF8b Accessory Protein Suppresses Type I IFN Expression by Impeding HSP70-Dependent Activation of IRF3 Kinase IKKε

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By Lok-Yin Roy Wong, Zi-Wei Ye, Pak-Yin Lui
| The Journal of Immunology Verified
Lok-Yin Roy Wong, Zi-Wei Ye, Pak-Yin Lui, Xuyang Zheng, Shuofeng Yuan, Lin Zhu, Sin-Yee Fung, Kit-San Yuen, Kam-Leung Siu, Man-Lung Yeung, Zongwei Cai, Patrick Chiu-Yat Woo, Kwok-Yung Yuen, Chi-Ping Chan and Dong-Yan Jin J Immunol September 15, 2020, 205 (6) 1564-1579; DOI: https://doi.org/10.4049/jimmunol.1901489 Key Points MERS-CoV ORF8b protein functions as a type I IFN antagonist. ORF8b-deficient MERS-CoV induces IFN and ISG expression more robustly.
Open in Who Shared Issue with article?

Middle East Respiratory Syndrome Coronavirus ORF8b Accessory Protein Suppresses Type I IFN Expression by Impeding HSP70-Dependent Activation of IRF3 Kinase IKKε

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By Lok-Yin Roy Wong, Zi-Wei Ye, Pak-Yin Lui, Xuyang Zheng
| The Journal of Immunology Verified
Lok-Yin Roy Wong, Zi-Wei Ye, Pak-Yin Lui, Xuyang Zheng, Shuofeng Yuan, Lin Zhu, Sin-Yee Fung, Kit-San Yuen, Kam-Leung Siu, Man-Lung Yeung, Zongwei Cai, Patrick Chiu-Yat Woo, Kwok-Yung Yuen, Chi-Ping Chan and Dong-Yan Jin J Immunol August 3, 2020, ji1901489; DOI: https://doi.org/10.4049/jimmunol.1901489 Key Points MERS-CoV ORF8b protein functions as a type I IFN antagonist. ORF8b-deficient MERS-CoV induces IFN and ISG expression more robustly.
Open in Who Shared Issue with article?

PACT Facilitates RNA-Induced Activation of MDA5 by Promoting MDA5 Oligomerization

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By Pak-Yin Lui, Lok-Yin Roy Wong, Ting-Hin Ho, Chi-Ping Chan
| The Journal of Immunology Verified
PACT Facilitates RNA-Induced Activation of MDA5 by Promoting MDA5 Oligomerization Pak-Yin Lui, Lok-Yin Roy Wong, Ting-Hin Ho, Shannon Wing Ngor Au, Chi-Ping Chan, Kin-Hang Kok, Dong-Yan Jin The Journal of Immunology September 1, 2017, 199 (5) 1846-1855; DOI: 10.4049/jimmunol.1601493
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