Pakkirisamy Sivakumar

Rh(III)-catalyzed [4+1] annulation of sulfoxonium ylide with allyl alkyl ethers: A detailed theoretical study of DFT, anti-inflammatory and antidiabetic activity We propose an [4+1] annulation of sulfoxonium ylides with allyl ether by Rh(III)-which leads to the formation of alkyl-substituted indanone derivatives. The reactions occur under mild without external oxidant. The ylide serves as a traceless directing group in the subsequent annulation with allyl alkyl ethers via (4+1) annulation.

A synthesis and spectral characterization of 4-methylthiazole derivatives. DFT approach and biological activities Pakkirisamy Sivakumar, Bharanidharan Sarangapani, Rajaram Rajamohan, Balasubramaniyan Anandhan, Thangavelu Sumathi and Subramaniyan Kamatchi Abstract The design of organic molecules opt for drug molecules holds tremendous promise for success in both the present and future.