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Panthipa Supraditaporn

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Articles

Selective Tropism of Dengue Virus for Human Glycoprotein Ib

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By Nattapol Attatippaholkun, Nont Kosaisawe, Yaowalak U-Pratya, Panthipa Supraditaporn
| Nature Verified
Rapid depletion of platelet is one of the most common manifestations in dengue patient. Platelet is the late-stage of megakaryocyte-platelet development. Therefore, we firstly investigated the late-stage differentiation marker, CD42b. This marker starts being expressed from mature megakaryocytes to platelets24,25 (Fig. 1A). We double immunostained DENV-infected cells with CD42b-PerCP and DENV-PE. The processes how to define the quadrant were demonstrated in Fig. S1.
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