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CRISPRi knockdown of mycobacterial tkt gene potentiates the anti-mycobacterial activity of phyto-compounds from selected medicinal plants - BMC Complementary Medicine and Therapies

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By Mashilo Mash, Gabriel Tshwahla, Parow Cape Town
| link.springer.com
Abstract Mycobacterium tuberculosis (Mtb) infection is well known to be challenging to treat. Treatment effectiveness is restricted by the pathogen’s inherent drug resistance. A deeper understanding of essential bacterial pathways that influence Mtb growth and survival can expediate the development of more effective therapies from various sources.
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