Partigya Partigya

Unactivated alkylsulfinic acids as an alkyl radical source for the synthesis of 3,3-dialkylindolin-2-ones via an electron donor-acceptor complex Using unactivated alkylsulfinic acids as an alkyl radical source, a novel and highly practical visible-light-assisted synthetic methodology for the alkylation/annulations of a series of N-arylacrylamides into corresponding 3,3-dialkylindolin-2-ones has been developed.

Convenient synthesis of 2-chloro-3-substituted quinoxalines by visible-light-induced radical cascade cyclization of ortho-diisocyanoarenes with sulfinic acids 2-Chloro-3-substituted quinoxalines (3) are significant precursors in the synthesis of 2,3-di-unsymmetrically substituted quinoxalines, including quinacillin, which has been shown to be effective against a number of transplantable diseases and cancer cells.