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Pascal Boutinaud

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Articles by Pascal Boutinaud

Sphingomyelins in mosquito saliva reconfigure skin lipidome to promote viral protein levels and enhance transmission of flaviviruses

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By Hacène Medkour, Lauryne Pruvost, Elliott F. Miot, Xiaoqian Gong, Virginie Vaissayre, Mihra Tavadia, Pascal Boutinaud, Justine Revel, Atitaya Hitakarun, Wannapa Sornjai, Jim Zoladek, R. Duncan Smith, Sébastien Nisole, Justine Bertrand-Michel, Dorothée Missé, Guillaume Marti, Julien Pompon
| Cell Metabolism Verified
Keywords extracellular vesicles lipids dengue West Nile Zika Orthoflavivirus transmission bite unfolded protein response ERAD Introduction Several flaviviruses that cumulatively infect half a billion people annually, causing more than 120,000 fatalities and $9 billion in economic loss, are transmitted within mosquito saliva during biting.1 Nearly the entire human population is threatened by dengue virus (DENV), Zika virus (ZIKV), and West Nile virus (WNV), the most prevalent flaviviruses, due...
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