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Philipp Schulz , Pascal Migaud, Daniela Drauz, Sebastian Jaeger, Johannes Elias, and Hartmut Stocker Author affiliation: Joseph-Kliniken–St. Joseph Krankenhaus Berlin–Tempelhof, Berlin, Germany (P. Schulz, P. Migaud, D. Drauz, S. Jaeger, H. Stocker); Charité–Universitätsmedizin Berlin, Berlin (P. Schulz, P. Migaud, H. Stocker); MDI Limbach Berlin GmbH, Berlin (J. Elias); Health and Medical University Potsdam, Potsdam, Germany (J.
HLH in adults is characterized by fever, cytopenias, hepatosplenomegaly and hyperferritinemia, and carries a high mortality rate [1, 2]. It can occur secondary to infections, autoimmune diseases or malignancies, most commonly of haematological origin [1, 2]. Early identification of the underlying trigger is critical, but the sepsis-like presentation often delays diagnosis and worsens outcomes [3].
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