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Publication History Published online: November 05, 2018Accepted: November 4, 2018; Received in revised form: October 15, 2018; Received: June 14, 2018;
In Reply As Dr Thornton suggests, one of the strengths of our trial was the 100% follow-up and the 100% adherence to the treatment allocation in the pessary group. These high rates were obtained because all women included in the trial delivered at the study institution. Moreover, included women were extensively informed by the research staff about the risk of preterm delivery.
Question Does use of a cervical pessary reduce the rate of spontaneous delivery before 34 weeks of gestation among women with singleton pregnancies, short cervical length, and no prior spontaneous preterm birth? Findings In this randomized trial of 300 women, the rates of spontaneous preterm birth at less than 34 weeks were 7.3% with a cervical pessary compared with 15.3% without cervical pessary use, a significant difference.
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