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Patrice D Cani on Muck Rack

Patrice D Cani

Brussels
As seen in: Color Research & Application, Nature, Gut Journal, MDPI, Archives of Public Health, Science Magazine, Royal Society of Chemistry, BioRxiv, Cell Metabolism
Microbiota/Obesity/Diabetes. Discovered Metabolic Endotoxemia & Akkermansia health effects. Mediterranean/Sardinian.
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Articles

From microbiome to metabolism: Bridging a two-decade translational gap

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By Matthias Van Hul, Patrice D Cani
| Cell Metabolism Verified
Keywords intestinal clock sleep-wake cycle glutamine circadian rhythm Introduction: From the genome to the microbiome revolution The dawn of the 21st century coincided with a wave of optimism and elevated expectations in biomedical research, when it was announced that the human genetic code had been fully sequenced. Many hoped this landmark achievement would unveil the root causes of complex diseases and resolve many long-standing mysteries in medicine.
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Inhibition of IRAK4 by microbial trimethylamine blunts metabolic inflammation and ameliorates glycemic control - Nature Metabolism

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By Julien Chilloux, Amandine Everard, Petros Andrikopoulos, Liyong Zhang, Antonis Myridakis, Lesley Hoyles, Jose Maria Moreno-Navarrete, Jessica Luque, Laura Martinez-Gili, Lata Govada, Naomi E. Chayen, Robert Glen, Jeremy Nicholson, Massimo Federici, Jose Manuel Fernández-Real, Patrice D Cani, Christine Blancher, Sophie Calderari
| Nature Verified
Abstract The global type 2 diabetes epidemic is a major health crisis. Although the microbiome has roles in the onset of insulin resistance (IR), low-grade inflammation and diabetes, the microbial compounds controlling these processes remain to be discovered.
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Rapid modulation of gut microbiota composition by hypothalamic circuits in mice - Nature Metabolism

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By Miriam Toledo, Sara Martinez-Martinez, Elena Eyre, Jordi Altirriba, Macarena Pozo, Iñigo Chivite, Roberta Haddad-Tóvolli, Sergio R. Llana, Erika Monelli, Markus Schwaninger, Patrice D Cani, Rubén Nogueiras, Berta Laudo
| Nature Verified
Abstract In recent years, the gut microbiota and derived metabolites have emerged as relevant players in modulating several brain functions, including energy balance control1,2,3. This form of distant communication mirrors that of metabolic hormones (for example, leptin, ghrelin), which convey information about the organism’s energy status by exerting effects on diverse brain regions, including the master homeostatic centre, the hypothalamus4.
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