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Patricia J. Hare on Muck Rack

Patricia J. Hare

As seen in: Cell Press, Dialnet - Universidad de La Rioja
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Articles by Patricia J. Hare

Science starts at the dinner table: Building STEM connections with families

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By Patricia J. Hare
At a family science event in Hartford, a volunteer used salt-dough bones and modeling clay to show how cartilage protects joints.
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Non-canonical double-stranded DNA break repair in Pseudomonas aeruginosa includes LigD-independent non-homologous end joining

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By Patricia J. Hare, Juliet R González, Anna Truong
| Dialnet - Universidad de La Rioja
Pseudomonas aeruginosa is a highly adaptive Gram-negative pathogen that is commonly managed with fluoroquinolone (FQ) antibiotics. Even without heritable resistance mutations, FQ-susceptible cells of P. aeruginosa can survive treatment in a phenomenon termed antibiotic persistence.
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Three subtypes of lung cancer fibroblasts define distinct therapeutic paradigms

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By Byrne C.J, Haichuan Hu, Zofia Piotrowska, Patricia J. Hare
| Cell Press Verified
Highlights • A living biobank of CAFs from NSCLC patients recapitulates clinical CAF heterogeneity • Therapeutic profiling of the NSCLC CAFs reveals three distinctive functional subtypes • Subtype I and II CAFs have high HGF and FGF7 expression and protect cancer cells • Subtype III CAFs associate with better clinical response and immune cell migration Summary Cancer-associated fibroblasts (CAFs) are highly heterogeneous.
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